Neo-Adjuvant Chemotherapy and Conservative Surgery in Cervical Cancer to Preserve Fertility.

Studie opzet en behandeling

FIGO 2018 stadium IB2 cervixca 2-4 cm
LNN dissectie>NACT>conisatie of simpele portio amputatie

Primair eindpunt

  • Primary objective is to determine the efficacy of neo-adjuvant chemotherapy to reduce tumour size below 2 cm in diameter and thus enabling less radical surgery
  • Same time safety, defined as number of women who get recurrence within two years, after LRS will be monitored continuously.

Aantal benodigde patiënten



Nienke van Trommel

Frederik Amant

Ko van de Velden


Deelnemende centra: CGOA / LUMC / UMCU / RadboudUMC